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Antioxidants cause malignant melanoma to metastasize faster: A strategic question

07/01/2016


Fresh research at Sahlgrenska Academy has found that antioxidants can double the rate of melanoma metastasis in mice.

The results reinforce previous findings that antioxidants hasten the progression of lung cancer. According to Professor Martin Bergö, people with cancer or an elevated risk of developing the disease should avoid nutritional supplements that contain antioxidants.

Researchers at Sahlgrenska Academy, University of Gothenburg, demonstrated in January 2014 that antioxidants hastened and aggravated the progression of lung cancer. Mice that were given antioxidants developed additional and more aggressive tumors. Experiments on human lung cancer cells confirmed the results. Given well-established evidence that free radicals can cause cancer, the research community had simply assumed that antioxidants, which destroy them, provide protection against the disease. Found in many nutritional supplements, antioxidants are widely marketed as a means of preventing cancer.

Because the lung cancer studies called the collective wisdom into question, they attracted a great deal of attention. Double the rate The follow-up studies at Sahlgrenska Academy have now found that antioxidants double the rate of metastasis in malignant melanoma, the most perilous type of skin cancer. Science Translational Medicine published the findings on October 7.

“Antioxidants Can increase Melanoma Metastasis in Mice” was published in Science Translational Medicine on October 7. Contact the author if you would like to obtain a copy of the article.